Nope, unfortunately not.
Healing reduction is capped at -40%, no number of cumulative effects can be greater than this, and only individual effects (such as Lingering Curse) can break this cap.
So, if you cast Defile Flesh and Malign Intervention on a target, they'll be at -40% healing reduction. however, if you cast Lingering Curse, it would override these effects, and leave the target with -50% reduction.
Hope I was clear enough...
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